Treatment of couples with unexplained subfertility and an unfavourable prognosis. A randomised trial comparing the effectiveness of IUI with ovarian hyperstimulation and IVF with single embryo transfer.

Not provided0 sites100 target enrollmentTBD

Conditionsnexplained subfertility or mild male subfertility

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: nexplained subfertility or mild male subfertility
Sponsor: Not provided
Enrollment: 100
Status: Recruiting
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

2 years ago

Study Type

Interventional

Investigators

Sponsor

Not provided

Eligibility Criteria

Inclusion Criteria

•1\. Female age between 18 and 36 years;
•2\. Couples must be diagnosed with unexplained subfertility, defined as normal semen (pre\-wash total motile sperm count of at least 40 million), spontaneous ovulatory cycle and patent Fallopian tubes, or with mild male subfertility, defined as a post\-wash total motile sperm count above 3 million;
•3\. The couple has poor fertility prospects as calculated by the validated model of Hunault (Hunault et al., 2005, Van der Steeg et al., Submitted). A poor fertility prospect is defined as a chance of spontaneous pregnancy below 30% within 12 months.

Exclusion Criteria

•1\. Polycystic ovary syndrome;
•2\. Endocrinopathological disease like: Cushing syndrome, adrenal hyperplasia, hyperprolactinemia, acromegaly, imminent ovarian failure, premature ovarian failure, hypothalamic amenorrhea, hypothyroidy, diabetes mellitus type I;
•3\. If not willing or able to sign the consent form.

Outcomes

Primary Outcomes

Not specified

Similar Trials

Completed

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