NCT02514564已完成不适用
The Effects of Aerobic Exercise Training in Patients With Cardiovascular Diseases Related to Microvascular Endothelium Function, Angiogenesis, Oxidative Stress and Aerobic Capacity
Instituto Nacional de Cardiologia de Laranjeiras1 个研究点 分布在 1 个国家目标入组 115 人开始时间: 2014年12月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 115
- 试验地点
- 1
- 主要终点
- Changes in Skin microvascular blood flow
研究概览
简要总结
This study evaluates the effects of different volumes of aerobic exercise training in cardiovascular parameters of patients with cardiovascular diseases enrolled in a cardiac rehabilitation program.
详细描述
Aerobic exercise training is well known to improve endothelium dependent vasodilatation in the microcirculation. However, the impact of exercise frequency on this response in patients with coronary artery disease remains unclear.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •sedentarism for at least 6 months;
- •clinical diagnosis for coronary artery disease (occurrence of any acute coronary syndrome, including ST elevation or non-ST elevation myocardial infarction or unstable angina or by the diagnosis of obstructive coronary artery disease on coronary angiography in patients with stable angina).
排除标准
- •nephropathies;
- •decompensated cardiovascular diseases;
- •liver diseases.
结局指标
主要结局
Changes in Skin microvascular blood flow
时间窗: Change from baseline in skin microvascular blood flow at 6 months
Measured through a Laser Speckle Contrast Imaging equipment
次要结局
- Change in weight(Change from baseline in weight at 6 months)
- Change in peak oxygen consumption(Change from baseline in peak oxygen consumption at 6 months)
研究者
Juliana Pereira Borges
PhD
Instituto Nacional de Cardiologia de Laranjeiras
研究点 (1)
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