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临床试验/NCT02514564
NCT02514564已完成不适用

The Effects of Aerobic Exercise Training in Patients With Cardiovascular Diseases Related to Microvascular Endothelium Function, Angiogenesis, Oxidative Stress and Aerobic Capacity

Instituto Nacional de Cardiologia de Laranjeiras1 个研究点 分布在 1 个国家目标入组 115 人开始时间: 2014年12月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
115
试验地点
1
主要终点
Changes in Skin microvascular blood flow

研究概览

简要总结

This study evaluates the effects of different volumes of aerobic exercise training in cardiovascular parameters of patients with cardiovascular diseases enrolled in a cardiac rehabilitation program.

详细描述

Aerobic exercise training is well known to improve endothelium dependent vasodilatation in the microcirculation. However, the impact of exercise frequency on this response in patients with coronary artery disease remains unclear.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
40 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • sedentarism for at least 6 months;
  • clinical diagnosis for coronary artery disease (occurrence of any acute coronary syndrome, including ST elevation or non-ST elevation myocardial infarction or unstable angina or by the diagnosis of obstructive coronary artery disease on coronary angiography in patients with stable angina).

排除标准

  • nephropathies;
  • decompensated cardiovascular diseases;
  • liver diseases.

结局指标

主要结局

Changes in Skin microvascular blood flow

时间窗: Change from baseline in skin microvascular blood flow at 6 months

Measured through a Laser Speckle Contrast Imaging equipment

次要结局

  • Change in weight(Change from baseline in weight at 6 months)
  • Change in peak oxygen consumption(Change from baseline in peak oxygen consumption at 6 months)

研究者

发起方
Instituto Nacional de Cardiologia de Laranjeiras
申办方类型
Other
责任方
Principal Investigator
主要研究者

Juliana Pereira Borges

PhD

Instituto Nacional de Cardiologia de Laranjeiras

研究点 (1)

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