Effects of Task-oriented Training on Functional Mobility and Fatigue in Patients With Multiple Sclerosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 34
- 主要终点
- Functional capacity
研究概览
简要总结
Multiple Sclerosis (MS) is inflammatory, demyelinating and autoimmune disease of the central nervous system. It is usually seen with relapses and genetic and environmental factors play a role in the etiology. Neurological symptoms seen in MS restrict the patient's daily activity and social role participation. Mobility problems and fatigue are the most important reasons of role limitations and decreased quality of life. The importance of exercise training in disease management has been emphasized in recent years. However, few studies have investigated the effects of task-oriented trainings on symptoms of the disease. The aim of this sudy is to investigate the effects of task-oriented training additional to combined exercise training on functional capacity, mobility, balance, fatigue and quality of life in patients with MS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Multiple Sclerosis diagnosis
- •Expanded Disability Status Scale > 5,5
- •No cognitive problems
- •No relapses in the last 3 months
- •No other neurological or chronic disease
排除标准
- •Relapse during the intervention
- •Exercise intolerance
研究组 & 干预措施
Control group
Patients in this group will receive combined exercise training included aerobic and strengthening exercises, 3 times a week for 6 weeks. All exercise sessions will be performed under the supervision of a physiotherapist.
干预措施: Combined exercise training (Other)
Training group
Patients in this group will receive task-oriented training additional to combined exercise training 3 times a week for 6 weeks. Task-oriented training included more functional daily life mobility activities like reaching, obstacle walking, stairs climbing. All exercise sessions will be performed under the supervision of a physiotherapist.
干预措施: Task-oriented training (Other)
结局指标
主要结局
Functional capacity
时间窗: 6 weeks
Change from baseline functional capacity with six minute walking test
次要结局
- dynamic gait skills(6 weeks)
- limitation of gait(6 weeks)
- dynamic balance and fall risk(6 weeks)
- sitatic balance(6 weeks)
- dynamic balance(6 weeks)
- severity of fatigue(6 weeks)
- impact of fatigue(6 weeks)
- Quality of life(6 weeks)
研究者
Kamer Unal
Lecturer, PhD, PT
Bezmialem Vakif University