Diazoxide-Mediated Insulin Suppression in Hyperinsulinemic Obese Men, part III.
- Conditions
- Hyperinsulinemic men with BMI 30-35 kg/m2MedDRA version: 9.1Level: LLTClassification code 10029883Term: Obesity
- Registration Number
- EUCTR2007-003244-30-NL
- Lead Sponsor
- Rijnstate Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- Male
- Target Recruitment
- Not specified
Inclusion Criteria
-Men
-BMI 30-35 kg/m2
-Age 25-50 years
-Healty
-Stable body weight 3 months before participating in study
-Fasting glucose = 6.0 mmol/L
-Fastinge C-peptide = 1.0 nmol/L or in upper quartile of normal
-HbA1c = 6.0%
-No co-medication.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
-creatinin > 120 µmol/L
-Liver enzyms > 2x upper limit of normal
-Gout
-Alcohol > 2E/day
-Drugs abuse
-Cessation of smoking less than 6 months before participating in study
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method