Effect of an herbal gel for the prevention of acute radiation dermatitis in patients with cancer: an open-label randomized clinical trial
Phase 2
Completed
- Conditions
- radiation dermatitis
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
The eligible patients were aged =18 years with pathologically confirmed breast, lung, or head and neck cancer of any stage, and scheduled to receive RT for =4 weeks.
Exclusion Criteria
The exclusion criteria were prior RT or serious lesions on the skin in the treatment area, poor Eastern Cooperative Oncology Group (ECOG) performance status score (>2), pregnancy or lactation, severe or uncontrolled systemic disease or infection, known allergy or hypersensitivity to gels, significant psychiatric disturbance, drug addiction, or alcohol dependence.
Study & Design
- Study Type
- Prevention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the herbal gel's efficacy in preventing acute radiation dermatitis in cancer patients?
How does the herbal gel compare to standard-of-care treatments like aloe vera or corticosteroids for radiation dermatitis prevention?
Are there specific biomarkers that predict response to herbal gel interventions in radiation dermatitis management?
What are the potential adverse events associated with herbal gel use in radiation dermatitis prevention and how are they managed?
What are the key components of the herbal gel and how do they synergize with existing radiation dermatitis therapies?