The efficacy of combination uses of pre-serum gel containing sodium hyaluronate and sodium ascorbyl phosphate with subcutaneous injection of hyaluronic filler: A split-face pilot randomized controlled study.
Phase 4
Recruiting
- Conditions
- Healthysodium hyaluronate, sodium ascorbyl phosphate, hyaluronic filler
- Registration Number
- TCTR20210629001
- Lead Sponsor
- Galderma (Thailand)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
1. Thai healthy volunteers aged equal to or more than 20 years
2. Patients who can come to follow up
Exclusion Criteria
1. Patients who are pregnant, lactating, and postpartum within 3 months
2. Patients with history of hyaluronic acid allergy
3. Patients with other skin diseases, or having infection at the area of face
4. Immunocompromised patients
5. Patients treated with laser, radiofrequency, and focus ultrasound on the face in the past 12 months
6. Patients treated with filler on the face in the past 12 months
7. Patients treated with chemical peeling, treatment with vitamin C in the past 1 month
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method skin hydration Baseline, 2 weeks, 1, 2, and 3 months after treatment. Corneometer
- Secondary Outcome Measures
Name Time Method indentation and maximum depth of wrinkle Baseline, 2 weeks, 1, 2, and 3 months after treatment. Antera analysis,Skin roughness Baseline, 2 weeks, 1, 2, and 3 months after treatment. Antera analysis,Physician improvement scale Baseline, 2 weeks, 1, 2, and 3 months after treatment. 6 points scale,Safety Baseline, 2 weeks, 1, 2, and 3 months after treatment. Adverse event