Symptoms in 2 methods of digoxin intake

Phase 3

• Conditions: arrhythmia, Heart failure.; Persistent atrial fibrillation

• Registration Number: IRCT20110512006463N2
• Lead Sponsor: Islamic Azad University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 July 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 77

Inclusion Criteria

Patients under treatment with digoxin for atrial fibrillation or heart failure, who were on a fixed regimen for at least two months prior to the trial and there were no need for any changes to the medications for any reason.

Exclusion Criteria

1-were hospitalized during the course of the trial because of pulmonary edema, worsening of the dyspnea or heart failure decompensation; 2-Needed any changes in other medications such as diuretics, beta-blockers because of worsening of symptoms or other reasons during the trial; 3-Had serum creatinine of more than 1 mg/dl or its increase to more than 1 mg/dl during the trial; 4-Suffered from chronic obstructive pulmonary disease (COPD); 5-Experienced considerable electrolyte imbalance6-Were not able to tolerate the medical regimen because of nausea, vomiting or other Digoxin intoxication symptoms

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Heart rate. Timepoint: 1 month. Method of measurement: Physical exam.;Palpitation score. Timepoint: 1 month. Method of measurement: 7 point visual score.;Dyspnea score. Timepoint: 1 month. Method of measurement: 1 to 7 point visual scoring system.