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A Study to assess the benefits and safety profile of the drug Saroglitazar in patients of non alcoholic fatty liver disease who are not obese(BMI less than 25)

Not Applicable
Conditions
Health Condition 1: K00-K95- Diseases of the digestive systemHealth Condition 2: K760- Fatty (change of) liver, not elsewhere classified
Registration Number
CTRI/2022/09/046081
Lead Sponsor
PGIMER CHANDIGARH
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Closed to Recruitment of Participants
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Patients with normal BMI ( >18 to < 25 kg/m2) diagnosed as NAFLD defined by the presence of hepatic steatosis on ultrasound or using CAP parameters (of FibroScan) in absence significant consumption of alcohol ( <20g/day) irrespective of gender after ruling out other etiologies of other etiologies for hepatic steatosis or elevated transaminases including but not limited to chronic viral hepatitis, autoimmune Hepatitis, hemochromatosis, Wilson disease, celiac disease, drug induced liver injury (DILI), etc. and having LSM <13.6 kPa

Exclusion Criteria

Patients with BMI >= 25 kg/m2, age <18 years or >75 years of age.

Patients with cirrhosis or with HCC or any other malignancy.

Patients with concomitant other etiologies for hepatic steatosis or elevated transaminases. Patients already on Vitamin E or pioglitazone.

Pregnant or lactating.

Patients too sick or not consenting to participate in the study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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