Comparison Between Bandage Contact Lens and Pressure Patching for The Erosion Area and Pain Scale in Corneal Erosion Patients

Udayana University1 site in 1 country32 target enrollmentSeptember 2012

ConditionsErosion; Cornea, Traumatic

Overview

Phase: Phase 3
Intervention: Not specified
Conditions: Erosion; Cornea, Traumatic
Sponsor: Udayana University
Enrollment: 32
Locations: 1
Primary Endpoint: Size of corneal erosion area
Status: Completed
Last Updated: 13 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This research aims to compare between bandage contact lens and pressure patching in reducing size of erosion area and pain scale in corneal erosion patients as well as its complications.

Detailed Description

This is a randomized open-label clinical trial in patients with mechanical corneal erosion. Subjects were selected to use bandage contact lens (Senofilcon A) or pressure patching. All subjects received combination of Polymyxin B, Neomycin, and Gramicidin eye drops and 0,5% Tropicamide eye drops. Evaluation was done 24 hours after treatment

Registry

clinicaltrials.gov

Start Date

September 2012

End Date

February 2013

Last Updated

13 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Udayana University

Responsible Party

Principal Investigator

Ni Nyoman Triharpini

Resident in Depatment of Ophthalmology Faculty of Medicine

Udayana University

Eligibility Criteria

Inclusion Criteria

•aged 17-55 years
•onset of corneal erosion \< 48 hours
•corneal erosion due to mechanical injury
•extensive corneal erosion \> 3 mm2

Exclusion Criteria

•bilateral corneal erosion
•corneal erosion due to chemical or thermal injury
•history of systemic analgesic use within 1 week prior to the examination or topical analgesics within 1 hour before the examination
•history of systemic or topical antibiotics within 1 week prior to the examination
•other abnormalities due to trauma
•palpebral or eyelashes position abnormalities
•anterior segment infections
•tear break-up time \< 7 seconds in the contra lateral eye

Outcomes

Primary Outcomes

Size of corneal erosion area

Time Frame: 24 hour

Corneal erosion area is the multiplication of the long and short axis of corneal erosion, as measured using a caliper, with the help of fluorescein and cobalt blue slit lamp beam