EUCTR2013-002439-10-GB
Active, not recruiting
Phase 1
Perioperative Analgesia for Knee Arthroplasty: A prospective randomised controlled trial - PAKA
niversity of Warwick0 sites264 target enrollmentOctober 18, 2013
ConditionsOsteoarthritis of the knee is a common problemit causes inability to walk without pain and a reduction in activity levels. Total knee replacements are performed for relief of this disabilitating condition and are the most common form of joint replacement in the NHS.MedDRA version: 17.0Level: LLTClassification code 10023476Term: Knee osteoarthritisSystem Organ Class: 100000004859Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Osteoarthritis of the knee is a common problem
- Sponsor
- niversity of Warwick
- Enrollment
- 264
- Status
- Active, not recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All patients undergoing an elective primary unilateral total knee arthroplasty under the care of an orthopaedic consultant at University Hospitals Coventry and Warwickshire NHS trust.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range: 0
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range 150
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range 100
Exclusion Criteria
- •A concomitant medical or psychiatric problem which, in the opinion of hte Investigator, would prevent completion of treatment or follow\-up; patients with a pre\-operative history neurological abnormality in the ipsilateral leg; patients with specific contraindication to the analgesia agents use; participation in a clinical trial of an investigational medicinal product in the last 90 days; previous entry in the present trial.
Outcomes
Primary Outcomes
Not specified
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