NCT02183922已完成不适用
Hypocaloric Diet With or Without Microencapsulated Fish Oil or Conjugated Linoleic Acid on Oxidative Stress and Cardiovascular Risk Factors in Women With Metabolic Syndrome Genotyped for Polymorphisms in the Genes PPAR Gamma 2 (Pro12Ala) and Adiponectin (G276T)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 37
- 试验地点
- 2
- 主要终点
- Oxidative stress biomarker
研究概览
简要总结
Our aim was to assess the effects of a hypocaloric diet, including diet fruit jelly with microencapsulated fish oil or conjugated linoleic acid or placebo, on anthropometry, body composition, insulin resistance and lipid profile in women with metabolic syndrome and genotype Pro12Pro in the PPAR gamma 2 gene.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 30 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •adults women (30-45 years old);
- •diagnosis of metabolic syndrome, as defined by the International Diabetes Federation;
- •Pro12Pro genotype in gene PPARγ2.
排除标准
- •Participants were excluded if they:
- •Were allergic to strawberries or fish
- •Were pregnant or lactating
- •Took fatty acid supplements
- •Had undergone bariatric surgery or were being treated nutritionally or pharmacologically for reducing BM, or had taken anti-obesity drugs during the previous three months
结局指标
主要结局
Oxidative stress biomarker
时间窗: Change from baseline at 12 weeks
Plasma malondialdehyde levels
次要结局
- Blood pressure(Change from baseline at 12 weeks)
- Insulin resistance(Change from baseline at 12 weeks)
- Lipid profile(Change from baseline at 12 weeks)
- Anthropometric measures(Change from baseline at 12 weeks)
- Body composition measures(Change from baseline at 12 weeks)
研究者
Sofia Kimi Uehara
Doctor
Universidade Federal do Rio de Janeiro
研究点 (2)
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