Cross-sectional study on determinants of contact dermatitis on the hands of construction workers: etiologic studies and development of a diagnostic tool

Completed

• Conditions: contact dermatitis; hand eczema; 10040789; 10001708; 10014982

• Registration Number: NL-OMON39572
• Lead Sponsor: niversiteit Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 1000

Inclusion Criteria

Construction workers

Exclusion Criteria

office personnel

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>* Occupational contact dermatitis (diagnosed by a team of a dermatologist and<br /><br>an occupational physician) is the main endpoint of the study.<br /><br>Other main study parameters are:<br /><br>* Contact dermatitis as diagnosed using a questionnaire<br /><br>* Atopic status (specific serum IgE to a panel of common allergens)<br /><br>* Mutations in the filaggrin gene (R501X, 2282del4, R2447X, S3247X, 3702delG)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Risk factors/predictors for OCD will be obtained by questionnaire. Questions<br /><br>will be asked on smoking status and a number of airway diseases that could be<br /><br>related to (atopic) dermatitis. In addition, questions are included on<br /><br>exposures to various products (e.g. paints, solvents, cement, etc.) to evaluate<br /><br>the risk of working with these products to realize the Stoffenmanger skin<br /><br>extension.</p><br>