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Prevention of catheter-related deep vein thrombosis with nadroparin in hemato-oncology patients treated with high dose chemotherapy

Completed
Conditions
Hemato-oncology patients with deep vein thrombosis
Circulatory System
Deep vein thrombosis
Registration Number
ISRCTN29686154
Lead Sponsor
Academic Medical Center (AMC) (The Netherlands)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
100
Inclusion Criteria

1. Central venous catheter
2. Indication for high dose chemotherapy (acute myeloid leukaemia [AML], acute lymphoblastic leukaemia [ALL], myelodysplasia-refractory anemia with excess of blasts in transformation [MDS-RAEB], multiple mye!oma [MM])
3. Informed consent

Exclusion Criteria

1. Current anticoagulant therapy
2. Allergy for contrastmedia
3.Promyelocytic leukemia (AML-M3)
4. Bleeding tendency
5. Renal failure

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Asymptomatic and symptomatic catheter-related deep vein thrombosis proven by ultrasound or venography
Secondary Outcome Measures
NameTimeMethod
1. Catheter-related infections<br>2. Bleeding complications
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