Comparison of USG guided platelet rich plasma Injection to corticosteroid injection in treatment of shoulder impingement
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- 1. Change from baseline of severity of symptoms and functional status using QDASH questionnaire
研究概览
简要总结
Shoulder impingement syndrome is most common cause of chronic shoulder pain
often causing limitation in range of movement at the shoulder joint. Shoulder’s
extreme mobility makes these symptoms cause great stress to the patient leading to
decreased quality of life. Rest, NSAIDs and physiotherapy have long been considered
the standard therapies in the majority of cases. However, there are limited treatment
options for the patients who are refractory to these conventional treatments and their
daily life activities are hindered due to the chronicity of symptoms. Corticosteroid
injections with their anti inflammatory effects have been used in such cases for short
term relief but it has some inherent disadvantages such as no long term effects,
infection, tendon ruptures, fat atrophy, etc. So there is need of newer agents that can
provide long-term effects and fewer side effects. Platelet rich plasma is a new
biological agent that has low side effects and can promote healing/regeneration. This
study aims to evaluate the effects of platelet rich plasma administered under USG
guidance and compare its efficacy in the treatment of such patients with shoulder
pathologies who are refractory to conventional treatment against old guard
recommendation of corticosteroids.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 19.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult patients having clinically diagnosed/suspected shoulder pathologies with refractory/recurrent pain and functional deficit for more than 2 months not resolving with conservative treatments i.e. NSAIDs and physiotherapy.
排除标准
- •â€¢ Pregnant patients • Patients having other causes of shoulder pain such as adhesive capsulitis, full thickness rotator cuff tears, major trauma, recurrent dislocations, osteoarthritis, inflammatory joint disease, cervical radiculopathy, thoracic outlet syndrome and bone tumors/ other malignancy at shoulder joint.
- •â€¢ Patients already diagnosed with neuromuscular disease or muscle disease.
- •â€¢ Patients with underlying coagulopathies, thrombocytopenia or taking anti-coagulant medications or having pace-maker.
- •â€¢ Patients with local site infection or localised dermatological condition.
- •â€¢ Patients who have recieved prior corticosteroid injection or have taken NSAIDs in last week(relative contra-indication).
- •â€¢ Patients who have undergone arthroscopic or open surgery of the affected shoulder, back or neck or have metallic implants in situ in the affected shoulder.
结局指标
主要结局
1. Change from baseline of severity of symptoms and functional status using QDASH questionnaire
时间窗: Evaluation will be done at baseline, 6 weeks and 12 weeks
in the two groups.
时间窗: Evaluation will be done at baseline, 6 weeks and 12 weeks
2. Change from baseline of pain using Visual Analogue Scale (VAS) in the two groups.
时间窗: Evaluation will be done at baseline, 6 weeks and 12 weeks
3. Change from baseline of range of movements using goniometer in the two groups.
时间窗: Evaluation will be done at baseline, 6 weeks and 12 weeks
4. Comparison of the improvement between the two groups.
时间窗: Evaluation will be done at baseline, 6 weeks and 12 weeks
次要结局
- 1. Comparison of improvement of quality of life after the completion of the treatment in both(groups using WORC.)
研究者
Rohit Krishna Dev
Guru Teg Bahadur hospital, University of medical sciences, new delhi