MedPath

Comparison of Human Insulin Produced by the Current Process and the NN729 Process in Type 1 Diabetes

Phase 3
Completed
Conditions
Diabetes Mellitus, Type 1
Diabetes
Registration Number
NCT00569400
Lead Sponsor
Novo Nordisk A/S
Brief Summary

This trial is conducted in Asia and Oceania. The aim of this trial is to compare the efficacy and safety of human insulin produced by the current process and the NN729 process in type 1 diabetes.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
241
Inclusion Criteria
  • Duration of diabetes for at least 12 months
  • Basal/bolus treatment with human insulin for at least 2 months preceding trial start
  • Body Mass Index (BMI) lesser than or equal to 35.0 kg/m2
  • HbA1c lesser than or equal to 12.0%
Exclusion Criteria
  • Proliferative retinopathy or maculopathy requiring acute treatment or laser treatment within the last 6 months
  • Any condition that the investigator and/or sponsor feel would interfere with trial participation
  • Known or suspected allergy against trial product or related products

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Change of human insulin antibodiesafter 26 weeks of treatment
Secondary Outcome Measures
NameTimeMethod
Frequency of adverse events
Change of human insulin antibodies

Trial Locations

Locations (1)

Novo Nordisk Investigational Site

🇵🇭

Marikina City, Philippines

© Copyright 2025. All Rights Reserved by MedPath