Skip to main content
Clinical Trials/NCT06767618
NCT06767618
Recruiting
N/A

Investigation of Upper Extremity Exercise Capacity, Hand Grip Strength and Daily Living Activities in Rheumatoid Arthritis Patients

Kirsehir Ahi Evran Universitesi1 site in 1 country60 target enrollmentJanuary 25, 2025

Overview

Phase
N/A
Intervention
Not specified
Conditions
Rheumatoid Arthritis
Sponsor
Kirsehir Ahi Evran Universitesi
Enrollment
60
Locations
1
Primary Endpoint
Evaluation of Upper Extremity Exercise Capacity
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

There are limited studies in the literature evaluating upper extremity functional exercise capacity, muscle functions and daily living activities in rheumatoid arthritis patients. In this context, the aim of this study was to investigate upper extremity exercise capacity, hand grip strength and daily living activities in rheumatoid arthritis patients.

Detailed Description

Rheumatoid arthritis is an inflammatory autoimmune chronic and systemic disease of unknown etiology. In addition to musculoskeletal involvement, lung involvement can also be observed in patients. Lung involvement and accompanying symptoms cause deterioration of physical function, quality of life and functional capacity. In rheumatoid arthritis, dyspnea can be observed during exertion due to disease progression, drug toxicity and respiratory/cardiovascular morbidities. In patients, decreased respiratory muscle strength, respiratory functions, carbon monoxide diffusion capacity and oxygen consumption also cause decreased physical functions. It has been reported that upper extremity exercise capacity and functional performance are reduced in patients with interstitial lung disease. It is known that peripheral muscle strength is an independent determinant of exercise capacity in interstitial lung disease. Rheumatoid cachexia, characterized by decreased muscle mass and increased fat mass, is observed in rheumatoid arthritis patients. Since the patients' accessory respiratory muscles are also affected, it can negatively affect their daily life activities, especially those that use the upper extremities.

Registry
clinicaltrials.gov
Start Date
January 25, 2025
End Date
January 25, 2027
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Kirsehir Ahi Evran Universitesi
Responsible Party
Principal Investigator
Principal Investigator

Başak KAVALCI KOL

Principal Investigator

Kirsehir Ahi Evran Universitesi

Eligibility Criteria

Inclusion Criteria

  • Inclusion criteria for patients with rheumatoid arthritis
  • Patients diagnosed with rheumatoid arthritis,
  • Between the ages of 18-75 years,
  • Patients who volunteer to participate in the study will be included in the study.
  • Inclusion criteria for the healthy control group
  • Between the ages of 18-75 years,
  • Volunteer to participate in the study will be included in the study.

Exclusion Criteria

  • Exclusion criteria for patients with rheumatoid arthritis
  • Those with serious cardiopulmonary, neurological, neuromuscular, orthopedic and other systemic diseases or other diseases affecting physical functions,
  • Those who have participated in a planned exercise program in the last three months
  • Those with cognitive impairment that will cause difficulty in understanding and following exercise test instructions
  • Patients with contraindications for exercise testing or exercise training according to the American Sports Medicine Association will not be included in the study.
  • Exclusion criteria for the healthy control group
  • Those with any diagnosed chronic or systemic disease,
  • Those who smoke 10 packs x years or more,
  • Those who have pneumonia or any acute infection,
  • Healthy individuals with any psychiatric disorder will not be included in the study.

Outcomes

Primary Outcomes

Evaluation of Upper Extremity Exercise Capacity

Time Frame: First day and second day

The six minute peg board and ring test will be used to assess upper extremity exercise capacity.

Glittre Activities of Daily Living

Time Frame: Second day

The Glittre activities of Daily Living test will be used to evaluate the daily living activities of individuals.

Secondary Outcomes

  • Evaluation of upper extremity functional status(First day)
  • Hand-grip strength(First day)
  • Evaluation of arm and shoulder muscle strength and endurance(Second day)

Study Sites (1)

Loading locations...

Similar Trials