Comparative clinical evaluation of Virechna by Trivutta Avaleha and Vidangatanduladi Yoga in the management of Sthoulya (Obesity)
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Percent change in bodyweight individually(5%).
研究概览
简要总结
In global problem, Obesity in Ayurveda has been described as Sthoulya or Medoroga.Sthoulya is one among the prevalent disease now a days due to change in lifestyle, Fast food, Over eating, Sedentary lifestyle, lack of exercises. Sthoulya if left untreated which provides the platform for so many other diseases like – Hypertension, Diabetes Mellitus, Coronary Heart Disease, Osteoarthritis, Infertility ,Impotency etc. and it can be life threatening. Hence it’s management in early stage is necessary to avoid further complications. Sthoulya is a disease resulting due to excessive incorporation of Kapha Vardhak and Medovardhak Aahar Vihara by a person. In Ayurveda, Sthoulya is described under names of SantarpanajanyaVikara, Ashtaunindita Purush, Shushma Nanatmaja Vyadhi and Medo Dhatupradoshaja Vikara.Virechan is one of the Pradhan Shodhan Karma to eliminate Tridosha and establish normal conditions (Dosha, Dhatu, Mala, Satmya Avastha ) in body.Trivrutta Avaleha is an Ayurvedic medicine having purgative properties. Trivrutta is regarded as the most effective drug for Sukhavirechana and Bhedan. It is a highly recommended drug that has proven to be a milestone in the commencement of Virechan Karma.In this study, Trivritta Avaleha will be used for Virechana Karma as a control group.Vidangatanduladi Yoga is having purgative properties. Vidangatanduladi Churna is palatable as it should be consumed with Madhu. As it is indicated to use in Kaphaj ,Vataj Vikar it can be used in Sthoulya. In the efficacy of drug it’s stated that both medicines are potent in managing disease of Sthoulya. In the particular study under standard measures we are going to compare the efficacy of both these drugs through Virechan in the disease of Sthoulya.Till now no comparative studies were performed on Virechan by Trivrutta Avaleha and Vidangatanduladi Yoga in Sthoulya. Here we are comparing efficacy of Trivrutta Avaleha and Vidangatanduladi Yoga as Virechana in Sthoulya.So to check its potency and efficacy as a Virechana drug in Sthoulya this study has been choosen.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients between age group of 18 to 50 years will be included.
- •Individuals having clinical signs and symptoms of Sthoulya.(Anga Gaura ,Utsah Hani Swedadhikya ,Anga Daurgandya.) 3)Individuals having BMI Above 27 kg/m² to 30 kg/m2 4)Those who will fit for Virechan Karma.
排除标准
- •Patients contraindicated for Virechan Karma, Pregnant women and lactating women.
- •Patients of known hypothyroidism or any hormonal imbalance disorder, psychological disorder, use of long-term steroid therapy or any weight loss medication.
结局指标
主要结局
Percent change in bodyweight individually(5%).
时间窗: At baseline (before treatment), after completion of Virechana, and during follow-up on 30th day and 45th day from Abhyantara Snehapana.
次要结局
- Reduction in: 1)(Anthropometric and body compositional parameters. 2)Biochemical parameters (High densitylipoprotein,Triglycerides))
研究者
DrDiksha Kharat
Bharati Vidyapeeth ( Deemed to be University)College of Ayurved ,Dhankawadi Pune
