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临床试验/DRKS00031457
DRKS00031457招募中Unknown

Validation of optical rhinometry and nasal nitric oxide measurement for clinical use in allergic and non-allergic patients based on acoustic rhinometry and active anterior rhinomanometry - VoRnNO Study

DGUV, Institut für Prävention und Arbeitsmedizin (IPA) Bochum0 个研究点目标入组 160 人开始时间: 2023年3月10日最近更新:

试验速览

阶段
Unknown
状态
招募中
发起方
入组人数
160

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Non-randomized controlled study
盲法
Open (masking not used)

入排标准

年龄范围
18 Years 至 55 Years(—)
性别
All

入选标准

  • No allergies (negative prick test, negative medical history, sX1 and IgE normal)
  • Birch pollen allergy (matching seasonal complaints, prick test positive for early bloomers and blood serum birch pollen sensitization detectable)
  • House dust mite allergy (suitable seasonal complaints, prick test and proof of sensitization in serum to Derm pter. and/or farinae detectable)

排除标准

  • active smoking
  • High blood pressure & medication with ACE inhibitors and/or beta blockers
  • pregnancy/breastfeeding
  • known severe reactions to histamine
  • history of anaphylactic reaction (allergic shock)
  • systemic cortisone medication < 3 weeks
  • medication with antihistamines < 3 weeks
  • Polyposis nasi
  • infection less than four weeks ago
  • local allergic rhinopathy
  • nonspecific nasal hyperreactivity

研究者

发起方
DGUV, Institut für Prävention und Arbeitsmedizin (IPA) Bochum

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