ACTRN12623001237673尚未招募2 期
Assessment of the effect of Empagliflozin on sympathetic tone and extra-renal effects in anuric haemodialysis patients using microneurography
Dobney Hypertension Centre0 个研究点目标入组 20 人开始时间: 2023年11月30日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Adults 18 years and older
- •Anuric haemodialysis patients
- •Able to mobilise independently
- •BP <160/90 mmHg
排除标准
- •Patients with Type 1 Diabetes
- •Patients on SGLT2-inhbitors prior to the study will be excluded.
- •History of Unilateral or Bilateral Nephrectomy, chronic liver disease, heart failure [New York Heart Association (NYHA) class II-IV}, or secondary hypertension
- •Pregnancy (females of childbearing potential must have negative pregnancy test)
- •Relative or absolute contraindication to empagliflozin, including active urinary or genital tract infection, or known drug allergy
- •Severe peripheral vascular disease or neuropathy
- •Initiation of alpha-blockers, beta-blockers or moxonidine within the preceding 6 weeks
- •Cardiovascular event(s) within the last 6 months
- •Unstable psychiatric condition or inability to understand and attend appointments
- •On medications such as corticosteroids, multiple antidepressants, and antipsychotics
研究者
相似试验
尚未招募
3 期
Evaluation of the effect of Empagliflozin on the severity of heart failure symptoms and echocardiography parameters in patients with congenital heart diseases with left-to-right shuntIRCT20120520009801N11Mashhad University of Medical Sciences44
招募中
3 期
Effect of Empagliflozin in PrediabetesCondition 1: Impaired fasting glucose. Condition 2: Impaired glucose tolerance.Impaired fasting glucoseImpaired glucose tolerance (oral)R73.01R73.02IRCT20220902055858N1Shahre-kord University of Medical Sciences90
已完成
3 期
Effect of Empagliflozin in prevention of kidney stone parametersIRCT20211203053261N2Hamedan University of Medical Sciences138
已完成
1 期
Empagliflozin in non alcoholic fatty liverDiabetic patient with non alcoholic fatty liver.Other specified inflammatory liver diseasesK75.8IRCT20150706023084N18Islamic Azad University30
招募中
2 期
Evaluation of the effect of empagliflozin on prevention of atrial fibrillation after heart surgeryAtrial fibrillation after heart surgery.Paroxysmal atrial fibrillationIRCT20120520009801N9Mashhad University of Medical Sciences160