Reliability of heart rate variability parameters as correlates of interoception and pai

Not Applicable

Conditions: heart rate variability, interoception, pain, respiratory sinus arrhythmia, experimental pilot study, reliability.

Registration Number: DRKS00034187

Lead Sponsor: Dresden International University in Kooperation mit der Osteopathie Schule Deutschland

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 70

Inclusion Criteria

Language skills in German or English, free of serious chronic or acute illnesses, test persons must be able to see and count, non-smokers.

Exclusion Criteria

Known cardiovascular diseases (such as: Hypertension, hypotension, arrhythmias, heart attack, stroke, etc.), Acute respiratory disease (such as: viral infection, bacterial infection), Severe chronic respiratory disease (such as: COPD, bronchial asthma, respiratory tumours, chronic bronchitis, etc.), Pregnancy, drug or tobacco use and alcoholism, Serious neurological or mental disorders that could affect participation (such as: Multiple sclerosis, anxiety disorders, obsessive-compulsive disorders, severe depression etc.), Acute or chronic pain (such as: injuries, sore muscles, nerve pain, pain condition lasting >3 months, etc.), Cardiovascular medication (ACE inhibitors, beta-blockers, antiarrhythmics, anticoagulants etc.), Pain medication (opioid analgesics, non-opioid analgesics, antidepressants etc).

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HRV data (heart rate variability): LF (Low Frequency), HF (High Frequency), Log_LF (Logarithm of Low Frequency), Log_HF (Logarithm of High Frequency), LF/HF_ratio (Low Frequency/High Frequency Ratio), Log_RSA (Logarithm of Respiratory Sinus Arrhythmia), RMSSD (Root Mean Square of Successive Differences), pNN50 (Percentage of Successive NN Intervals That Differ by More Than 50 ms), EDR (ECG derived respiratory signal). <br>Interoceptive accuracy (IAcc) and interoceptive focus (Insight). Questionnaires: IATS (Interoception Attention Scale), MAIA (Multidimensional Assessment of Interoceptive Awareness), IAS (Interoceptive Accuracy Scale), BPQ-SF (Body Perception Questionnaire -Short form). <br>Visual analogue scale for confidence rating of the heartbeat count (CR of the HCT) and visual analogue scale for pain intensity and pain unpleasantness of the Cold Pressor Test.

Secondary Outcome Measures

Name	Time	Method
HRV data (heart rate variability): RR (R-wave intervals of ECG), SDNN (Standard Deviation of NN intervals), VLF (very low frequency), VFL_Log (very low frequency Logarithm), Spectral Log_Power (Logarithm of spectral analysis), SD1 and SD2 (Standard Deviation 1 and 2), DFA Alpha 1 (Detrended Fluctuation Analysis Alpha 1).<br>Socio-demographic data by questionnaire.