Does vitamin D3 has any effect in preventing preeclampsia and its complication in pregnant females
Phase 4
- Registration Number
- CTRI/2023/08/056852
- Lead Sponsor
- BPS Govt. Medical College Khanpur Kalan, Sonipat
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Pregnant females who are willing to give written informed consent to participate in the study.
2. Pregnant females of age group 21-35 years with a singleton pregnancy and with a gestation age of 18-19 weeks.
Exclusion Criteria
1. Pregnant females who are unable or unwilling to give written informed consent.
2. Fetal abnormalities in the current or previous pregnancy
3. History of recurrent miscarriage
4. History of pre-eclampsia
5. History of hypertension
6. Twin pregnancy
7. Chronic kidney and liver disease
8. History of malignancy
9. Known case of osteomalacia
10. Recent history of therapeutic vitamin D3 consumption other than supplementation in the study
11. History of seizures
12. Known case of Diabetes mellitus
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pre-eclampsia assessment by blood pressure & proteinuriaTimepoint: Baseline 24 weeks, 28 weeks, 32 weeks & 36 weeks of gestation
- Secondary Outcome Measures
Name Time Method Serum vitamin D & calcium levels, kidney function tests, liver function tests, lipid profile and cordblood vitamin D levelsTimepoint: Baseline & 36 weeks