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The Impact of 3D-CBCT Imaging on Nerve Injuries During Wisdom Tooth Surgery

Not Applicable
Recruiting
Conditions
Inferior Alveolar Nerve Injuries
Impacted Third Molar Tooth
Interventions
Radiation: 3D-CBCT
Radiation: 2D-OPG
Registration Number
NCT06261853
Lead Sponsor
University of Aberdeen
Brief Summary

The investigators aim to investigate if the additional information available from a 3D scan of the wisdom tooth can reduce the risk of nerve injury during wisdom tooth surgery compared to conventional 2D images.

Wisdom tooth surgery is a common surgical procedures that a significant proportion of the population will undergo. As with any other surgical procedure, there are potential complications, of which, injury to the nerve supplying feeling to the lip, chin, and tongue is the most significant. This can lead to persistent pain, tingling, or numbness that may impact a patient's ability to eat and function.

The risk of nerve injury during wisdom tooth surgery is assessed using X-ray images, which show the position of the nerve and tooth in the jawbone. 2D and 3D scans are used, which have their own advantages and disadvantages such as reduced cost and radiation dose with 2D or more information from 3D images, but it remains unclear which is better at reducing the risk of nerve injuries.

Detailed Description

This pragmatic clinical trial is a multi-centre, two-arm, single-blind randomised controlled trial.

The primary research question is:

1. Does the additional information provided by a 3D scan, over a 2D x-ray, reduce the number of nerve injuries occurring during wisdom tooth surgery.

The secondary objectives are:

1. Does the additional information provided by the 3D scan, over the 2D x-ray, reduce the operation time?

2. Does the additional information provided by the 3D scan, over the 2D x-ray, impact the number and type of complications occuring during wisdom tooth surgery?

3. Does the additional information provided by the 3D scan, over the 2D x-ray, impact the number and type of complications observed after wisdom tooth surgery?

The study intervention:

1. On the day of surgery, the surgeon will utilise only one imaging technique, either the 2D OPG or the 3D CBCT, during wisdom tooth surgery. The trial arm allocation will be noted on their operating list alongside the planned procedure details. Conventionally, surgeons would have access to both images and therefore, it is difficult to determine the relative impact of each on surgical outcomes. The patient should observe no difference in their care in either arm of the trial on the day of surgery as they wouldn't typically be aware of which image was being utilised.

2. Data will be collected peri-operatively by way of a proforma completed by the surgeon. If the surgeon feels the need to use the other imaging modality to which the patient is allocated, for example, to maintain standards of care, this will be recorded along with the reasons why. Operating time and intraoperative complications will also be documented for each surgical procedure.

3. One week after the surgery, participants will receive a follow-up phone call from a research team member, which should last no more than five minutes. They will be asked five 'yes/no' questions about their recovery. Typically, patients having wisdom tooth surgery are not routinely followed up after their surgery unless specifically requested by the surgeon, therefore, this could be seen as an improved level of care for most patients especially as the research team member will have access to the post-operative care instructions from the department and can ask a surgeon to contact the patient if requested or deemed necessary.

4. After the one-week postoperative telephone review, the participant will be discharged from the study even if they continue to receive post-operative care, as clinically indicated, from their surgeon. If the patient is subsequently listed for another wisdom tooth surgical procedure and still meets the inclusion criteria, they may be invited to enrol again in the study.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
1292
Inclusion Criteria
  1. Individuals are seen in the Oral Surgery department with a 2D-OPG x-ray and a diagnosis of a mandibular wisdom tooth that requires surgical treatment.
  2. Individuals requiring a 3D-CBCT to further assess the relationship between the wisdom tooth and the inferior alveolar nerve.
  3. Individuals who are to undergo surgical treatment for their wisdom tooth regardless of the surgical approach (e.g. coronectomy or extraction) or the anaesthetic technique utilised.
  4. Individuals without any pre-existing neurological deficit of cranial nerve V (trigeminal nerve) or medical conditions or medications that may cause changes in neurosensory function.
  5. Individuals over the age of 16 and willing and able to provide valid informed consent for themselves.
  6. Individuals with adequate English comprehension to read the written PIS and consent form and understand the follow-up call questions.
  7. Individuals willing to provide contact details to allow a telephone follow-up call one week after their surgery.
Exclusion Criteria
  1. Individuals who do not have the capacity to consent for themselves.
  2. Individuals taking medicines or having medical conditions and disorders that impair neurosensory function.
  3. Individuals requiring wisdom tooth surgery to manage associated pathology such as cysts, fractures, or tumours where the pathological condition may interfere with the neurosensory function of the trigeminal nerve at 1 week post-operatively.
  4. Individuals who are unable to read or speak English.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
3D-CBCT Scan3D-CBCTThe surgeons will only utilise the 3D-CBCT scan of their patient during wisdom tooth surgery. The patient should observe no difference in their care in this arm of the trial on the day of surgery as they wouldn't typically be aware of which image was being viewed
2D-OPG X-ray2D-OPGThe surgeons will only utilise the 2D-OPG X-ray of their patient during wisdom tooth surgery. The patient should observe no difference in their care in this arm of the trial on the day of surgery as they wouldn't typically be aware of which image was being viewed
Primary Outcome Measures
NameTimeMethod
The number of patients reporting altered sensation in their lip and/or chin on the side of wisdom tooth surgeryone week after surgery

The primary outcome measure is assessed by a series of yes/no questions asked during the follow-up call one week after the surgery.

Secondary Outcome Measures
NameTimeMethod
Planned surgical approachon the day of surgery

Surgical technique utilised either total removal (extraction) or intentional partial removal leaving the roots behind (coronectomy). This will be measured and reported using data from the intraoperative surgeon's proforma which is completed by the surgeon on the day of surgery.

Wisdom tooth impaction classificationon the day of surgery

The classification of wisdom tooth impaction. This will be evaluated using data from the intraoperative surgeon's proforma which is completed by the surgeon on the day of surgery.

Surgical timeon the day of surgery

Surgery duration from initiation of the procedure (knife to mucosa or start of elevation etc. not including anaesthesia time) to the completion of closure of the wound (not including post-op instructions etc.). This will be evaluated using data from the intraoperative surgeon's proforma which is completed by the surgeon on the day of surgery.

Intraoperative complicationson the day of surgery

The quantity and type of intraoperative complications (excessive bleeding, unintentional root retention, nerve exposure). This will be evaluated using data from the intraoperative surgeon's proforma which is completed by the surgeon on the day of surgery.

Postoperative Complicationsone week after surgery

The quantity and type of postoperative complications (altered sensation in the tongue, persistent swelling, and analgesia intake). This will be evaluated using data collected from a series of yes/no questions asked during the follow-up phone call.

Trial Locations

Locations (2)

King'S College Hospital Nhs Foundation Trust

🇬🇧

London, England, United Kingdom

Aberdeen Dental Hospital

🇬🇧

Aberdeen, Scotland, United Kingdom

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