跳至主要内容
临床试验/CTRI/2024/04/065098
CTRI/2024/04/065098尚未招募1/2 期

Effect of Naturopathy based dietary intervention on the cardiovascular health index of sub clinical atherosclerosis.

Dr. Shalmali2 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2024年4月15日最近更新:

试验速览

阶段
1/2 期
状态
尚未招募
发起方
入组人数
80
试验地点
2
主要终点
Serum Lipid Profile

研究概览

简要总结

Cardiovascular disease (CVD) remain a leading cause of death globally. The concept of acute myocardial infarction in young adults was uncommon. Atherosclerosis is the leading cause of CVD, including myocardial infarction, stroke, heart failure and peripheral artery disease. This condition is initiated early in childhood and progressive in nature. CVD risk factors includes hypertension, dyslipidemia and obesity play a role in the development of atherosclerosis and components in insulin resistance syndrome

Data from seven observational studies suggest that subclinical atherosclerosis defined by increased cIMT or CACS is associated with an increased risk of incident Atrial Fibrillation. These findings emphasize the need for further research investigating whether treatment of subclinical atherosclerosis should be a part of the initiatives to prevent AF.[ Kristensen KE, Knage CC, Nyhegn LH, Mulder BA, Rienstra M, Van Gelder IC, Brandes A. Subclinical atherosclerosis is associated with incident atrial fibrillation: a systematic review and meta-analysis. Europace.

 Atherosclerosis starts early in life and progresses silently for decades. Considering atherosclerosis as a "systemic disease" invites the use of noninvasive methodologies to detect disease in various regions before symptoms appear.

The prevalence of subclinical atherosclerosis varies across body size phenotypes. Pharmacologic and lifestyle interventions might modify their cardiovascular risk by facilitating the transition from one phenotype to another. Therefore efforts are made to conduct scientific studies on effect of dietary interventions on cardiovascular health of people with subclinical atherosclerosis.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
30.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Atherogenic index greater than 0.21.

排除标准

  • History of Cardiovascular disease Any other systemic illness.

结局指标

主要结局

Serum Lipid Profile

时间窗: Pre data will be measured on day 1 and post data will be measure on day 91.

Complete Blood Count

时间窗: Pre data will be measured on day 1 and post data will be measure on day 91.

Fasting Blood Glucose

时间窗: Pre data will be measured on day 1 and post data will be measure on day 91.

Clinical Anthropometry

时间窗: Pre data will be measured on day 1 and post data will be measure on day 91.

次要结局

  • Clinical Anthropometry(Body composition analysis)

研究者

发起方
Dr. Shalmali
申办方类型
Other [Principal Investigator ]
责任方
Principal Investigator
主要研究者

DR SHALMALI

Shri Dharmasthala Manjunatheshwara College of Naturopathy and Yogic Sciences, Ujire

研究点 (2)

Loading locations...

相似试验