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Dutch Belgian randomised lung cancer screening trial (NELSON).

Conditions
lung cancer
Registration Number
NL-OMON22971
Lead Sponsor
- KWF Kankerbestrijding- ZONMW
Brief Summary

van Klaveren RJ, de Koning HJ, Mulshine J, Hirsch FR. Lung cancer screening by spiral CT. What is the optimal target population for screening trials? Lung Cancer 2002;38:243-52. <br><br> - van Klaveren RJ, Hirsch FR, van Iersel CA, Bunn PA. The selection of the optimal target population for spiral CT screening and chemoprevention trials. In: Hirsch FR, Bunn PA, Kato H, Mulshine JL, editors. Textbook of Prevention and Detection of Early Lung Cancer. Abingdon, Oxon, UK: Taylor & Francis; 2006. p. 361-384. <br><br> - van Iersel CA, de Koning HJ, Draisma G, Mali WPTM, Scholten ETh, Nackaerts K, Prokop M, Habbema JDF, Oudkerk M, van Klaveren RJ. Risk-based selection from the general population in a screening trial: selection criteria, recruitment and power for the Dutch-Belgian randomised lung cancer multi-slice CT screening trial (NELSON). Int J Cancer 2006; in press.

Detailed Description

Not available

Recruitment & Eligibility

Status
Other
Sex
Not specified
Target Recruitment
15600
Inclusion Criteria

1. Born between 1928 and 1956;

2a. Smoked > 15 cigarettes/day during > 25 years or;

Exclusion Criteria

Subjects

1. With a moderate or bad self-reported health who were unable to climb two flights of stairs;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
ung cancer mortality (reduction).
Secondary Outcome Measures
NameTimeMethod
1. Cost-effectiveness;<br /><br>2. Quality of Life.
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