Safety of the varying concentrations of milk feeds with food additives and medications
Not Applicable
Completed
- Conditions
- Osmolality of milk feedsNot Applicable
- Registration Number
- ISRCTN95873364
- Lead Sponsor
- Paediatric Academic Clinical Program
- Brief Summary
2016 Results article in https://pubmed.ncbi.nlm.nih.gov/28030867/ (added 18/11/2021)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 9
Inclusion Criteria
1. Aged 28 to 41 years
2. Delivered their infants preterm (<37 weeks of gestation)
3. Willing to donate their breast milk
Exclusion Criteria
Mothers who do not want to participate due to personal reasons.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Osmolality of expressed breast milk is measured using osmometer at baseline, when additives are added and 4 hours after additives are added.
- Secondary Outcome Measures
Name Time Method o secondary outcome measures
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link high-osmolality enteral feeds to gastrointestinal complications in preterm infants?
How do varying milk feed concentrations with food additives compare to standard enteral feeding in preterm infant safety outcomes?
Which biomarkers predict preterm infant tolerance to osmolality-modulated milk feeds in clinical practice?
What adverse events are associated with osmolality-increasing additives in neonatal enteral nutrition and how are they managed?
Are there combination therapies with osmolality-modulating agents to enhance preterm infant feeding safety and efficacy?