A phase IV, blinded, randomized controlled trial to compare the effectiveness of low pressure pneumoperitoneum during laparoscopic donor nephrectomy to optimize the quality-of-recovery during the early post-operative phase
- Conditions
- donor nephrectomykidney donation1003843010038365
- Registration Number
- NL-OMON40838
- Lead Sponsor
- niversitair Medisch Centrum Sint Radboud
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 64
Obtained informed consent
Age over 18 years
• insufficient control of the Dutch language to read the patient information and to fill out the questionnaires
• chronic use of analgetics or psychotropic drugs
• use of NSAIDs shorter than 5 days before surgery
• known of suspect allergy to rocuronium or sugammadex
• significant liver* or renal** dysfunction
• neuromuscular disease
• pregnant of breastfeeding;*Liver dysfunction is defined as alanine aminotransferase (ALAT) and/or aspartate aminotransferase (ASAT) > twice the upper limit (extremely rare in live kidney donors)
** renal dysfunction is defined as serum creatinine twice the normal level and/or glomerular filtration rate < 60 ml/min (extremely rare in live kidney donors)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Quality of recovery-40 score on day 1 (overall score)</p><br>
- Secondary Outcome Measures
Name Time Method