NCT03830957Unknown不适用
Randomized Clinical Trial of Ivabradine to Reduce Heart Rate Prior to Coronary CT-angiography in Advanced Heart Failure: Comparison With β-Blocker
Rajaie Cardiovascular Medical and Research Center1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2018年11月26日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Heart rate
研究概览
简要总结
The aim of this study is to compare the effects of Ivabradine and metoprolol to reduce heart rate prior to coronary CT angiography in patients with advanced heart failure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Sinus rhythm
- •Heart rate >60/min
排除标准
- •Atrial fibrillation
- •Any contraindication for beta-blocker use
研究组 & 干预措施
Ivabradine
Active Comparator
干预措施: Ivabradine (Drug)
metoprolol
Active Comparator
干预措施: Metoprolol (Drug)
结局指标
主要结局
Heart rate
时间窗: 30 minutes before and after coronary CT angiography
Changing heart rate during imaging study
次要结局
- Dyspnea(30 minutes before and after coronary CT angiography and 6 months later)
- Blood pressure, systolic and diastolic(30 minutes before and after coronary CT angiography and 6 months later)
- Hypotension(30 minutes before and after coronary CT angiography)
- Sleep quality(Before CT angiography and 6 months later)
- Functional calss(30 minutes before and after coronary CT angiography and 6 months later)
- Appetite(Before CT angiography and 6 months later)
- Prolonged bradycardia(30 minutes before and after coronary CT angiography)
研究者
研究点 (1)
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