Epicardial Adipose Tissue Thickness and the Related Factors in Patients With Ankylosing Spondylitis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 61
- 试验地点
- 1
- 主要终点
- Epicardial adipose tissue thickness
研究概览
简要总结
The aim of this study was to assess the EATT and the related factors in patients with AS and to compare the results with that of the healthy controls'
详细描述
The aim of this study was to investigate the epicardial adipose tissue thickness (EATT) and the related factors in patients with ankylosing spondylitis (AS) and to compare the results with those of the healthy controls. This cross-sectional study comprised thirty patients diagnosed with AS based on the modified New York criteria. The control group consisted of 31 healthy volunteers. Demographic characteristics were recorded. EATT was measured via transthoracic echocardiography. Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Ankylosing Spondylitis Disease Activity Score (ASDAS), Ankylosing Spondylitis Quality of Life (ASQoL), International Physical Activity Questionnaire Short Form (IPAQ-Short Form) were used. Functional capacity assessment was conducted using the six-minute walk test (6MWT).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Disease duration >1 year,
- •Being ≥18 years
- •AS diagnosis according to modified New York Criteria
排除标准
- •Being illiterate,
- •>65 years,
- •History of ischemic heart disease,
- •Cerebrovascular disease,
- •Hypertension,
- •Chronic kidney failure,
- •endocrinopathies like diabetes mellitus,
- •hypothyroidism,
- •Cushing syndrome and primary hyperlipidemia.
结局指标
主要结局
Epicardial adipose tissue thickness
时间窗: through study completion, an average of 5 months
Epicardial adipose tissue thickness is measured via transthoracic echocardiography
次要结局
- Bath Ankylosing Spondylitis Metrology Index(through study completion, an average of 5 months)
- Ankylosing Spondylitis Disease Activity Score(through study completion, an average of 5 months)
- Ankylosing Spondylitis Quality of Life(through study completion, an average of 5 months)
- International Physical Activity Questionnaire Short Form(through study completion, an average of 5 months)
- Bath Ankylosing Spondylitis Functional Index(through study completion, an average of 5 months)
- Six minute walk test(through study completion, an average of 5 months)
- Bath Ankylosing Spondylitis Disease Activity Index(through study completion, an average of 5 months)