Comparison of transdermal fentanyl and buprenorphine patch in pain management in hysterectomy patients

Phase 4

Conditions: Health Condition 1: O- Medical and Surgical

Registration Number: CTRI/2024/04/064971

Lead Sponsor: Himalayan Institute of Medical Sciences, Swami Rama Himalayan University

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

Age 18 to 60 years. Female patients. Patients undergoing radical abdominal hysterectomy. Written informed consent by patients. Grades 1 and 2 of the American Society of Anesthesia physical status.

Exclusion Criteria

1.Pregnant females.

2.Patients with history of pre-existing lung and cardiac disease.

3.Patients with impaired kidney or liver function.

4.Patients who have experienced an upper respiratory illness in the prior four weeks.

5.Patients with history of smoking, respiratory or gastrointestinal infection.

6.Patients with history of any allergy to any study drug.

7.Patients on antiepileptics or antidepressants, NSAIDS, or any type of pain medicine for longer than three months.

8.Patients with any syndrome of chronic pain.

9.Inability to understand pain assessment.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate and compare the effectiveness of fentanyl patch and buprenorphine patch in controlling immediate postoperative pain using Numerical rating scaleTimepoint: 72 hours from recovery of anesthesia

Secondary Outcome Measures

Name	Time	Method
Hemodynamic fluctuation and the side effects of fentanyl and buprenorphine patches by using Bellville grading scale for nausea and vomiting, and Ramsay sedation score for sedationTimepoint: 72 hours from recovery of anesthesia