Automated virtual reality (VR) cognitive therapy for patients with psychosis who have anxious avoidance of social situations: a single-blind parallel group randomised controlled trial (gameChange)
概览
- 阶段
- 未知
- 干预措施
- 未指定
- 疾病 / 适应症
- Clinical diagnosis of schizophrenia spectrum psychosis (F20-29) or an affective diagnosis with psychotic symptoms (F31.2, 31.5, 32.3, 33.3) (ICD-10, WHO, 2010)
- 发起方
- niversity of Oxford
- 入组人数
- 346
- 状态
- 已完成
- 最后更新
- 去年
概览
简要总结
2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/31462489 protocol (added 30/08/2019) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35395204/ (added 02/09/2022) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36399379/ Economic analysis (added 21/11/2022) 2023 Results article in https://doi.org/10.2196/38065 Qualitative results (added 17/01/2023) 2021 Protocol article in https://doi.org/10.2196/31742 Automated Virtual Reality Cognitive Therapy for People With Psychosis: Protocol for a Qualitative Investigation Using Peer Research Methods (added 24/06/2024) 2020 Protocol article in https://doi.org/10.2196/20300 Virtual Reality Cognitive Therapy in Inpatient Psychiatric Wards: Protocol for a Qualitative Investigation of Staff and Patient Views Across Multiple National Health Service Sites (added 24/06/2024) 2022 Results article in https://doi.org/10.2196/20300 Agoraphobic avoidance in patients with psychosis: Severity and response to automated VR therapy in a secondary analysis of a randomised controlled clinical trial (added 24/06/2024) 2022 Results article in https://doi.org/10.1017/s0033291722001167 Virtual reality (VR) therapy for patients with psychosis: satisfaction and side effects (added 24/06/2024)
研究者
入排标准
入选标准
- •1\. Adults aged 16 years or older
- •2\. Attending a NHS mental health trust for the treatment of psychosis
- •3\. Clinical diagnosis of schizophrenia spectrum psychosis (F20\-29\) or an affective diagnosis with psychotic symptoms (F31\.2, 31\.5, 32\.3, 33\.3\) (ICD\-10, WHO, 2010\)
- •4\. Having self\-reported difficulties going outside their home primarily due to anxiety that they would like treated
- •5\. Participant is willing and able to give informed consent for participation in the trial
排除标准
- •1\. Unable to attempt an Oxford\-Behavioural Assessment Task (O\-BAT) (the primary outcome measure) at baseline (e.g. due to being unpermitted to leave a psychiatric ward)
- •2\. Photosensitive epilepsy
- •3\. Significant visual, auditory, or balance impairment
- •4\. Current receipt of another intensive psychological therapy (or about to start it within the 6\-week trial therapy window)
- •5\. Insufficient comprehension of English
- •6\. In forensic settings or Psychiatric Intensive Care Unit (PICU)
- •7\. Organic syndrome
- •8\. Primary diagnosis of alcohol or substance disorder or personality disorder
- •9\. Significant learning disability
- •10\. Current active suicidal plans
结局指标
主要结局
未指定