NCT05775354
Enrolling By Invitation
Not Applicable
Reviving Early Diagnosis of Cardiovascular Disease in the Utrecht Health Project
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Coronary Artery Disease
- Sponsor
- UMC Utrecht
- Enrollment
- 1476
- Locations
- 1
- Primary Endpoint
- Coronary artery disease
- Status
- Enrolling By Invitation
- Last Updated
- 2 years ago
Overview
Brief Summary
The goal of this randomized trial is to compare the diagnostic yield of a screen-like early diagnosis strategy to usual primary care to detect coronary artery disease (CAD), atrial fibrillation (AF), heart failure (HF), and/or valvular heart disease (VHD) in community people aged 50-80 years who participate in the Utrecht Health Project.
The diagnosis strategy consists of a questionnaire with questions related to symptoms suggestive of CAD, AF or HF, a focused physical examination, laboratory testing, electrocardiography, and echocardiography.
Investigators
Monika Hollander, MD, PhD
MD, PhD
UMC Utrecht
Eligibility Criteria
Inclusion Criteria
- •Aged 50-80 years
- •Being a participant of LRGP
- •Having indicated in the LRGP informed consent to be interested in participating in further research.
Exclusion Criteria
- •Diagnosed with coronary artery disease and atrial fibrillation and heart failure.
- •Undergoing major (cardiovascular) surgery, and/or revascularisation therapy and/or transplantation treatment within 3 months after enrolment.
- •Not willing to give written informed consent for RED-LRGP.
- •Not allowing incidental findings to be reported to him/herself or their own GP.
Outcomes
Primary Outcomes
Coronary artery disease
Time Frame: 1 year
Atrial fibrillation
Time Frame: 1 year
Heart failure
Time Frame: 1 year
Valvular heart disease
Time Frame: 1 year
Secondary Outcomes
- CVD family history and women's reproductive history(1 year)
- Echocardiographic abnormalities(1 year)
- Health-related quality of life(1 year)
- Cardiovascular risk profile(1 year)
- Costs(1 year)
Study Sites (1)
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