Prehospital Management of Hypotensive Trauma in HEMS
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 500
- 试验地点
- 15
- 主要终点
- 30 days mortality
研究概览
简要总结
Up to today, inadequate evidences and knowledge exist about the best prehospital management of hypotensive trauma patients and its clinical consequence on the in-hospital recovery and mortality.
Also new emerging therapies such as prehospital blood transfusion and REBOA (resuscitative endovascular balloon occlusion of the aorta) are lacking strong evidences in, eventually, reducing hospital mortality and improving outcomes.
Moreover, prehospital emergency medicine is throughout Italy an heterogeneous system that has no unique standard operating procedures and, even among HEMS (helicopter emergency medical service), management and therapies on complex trauma patients may vary upon local policies.
With this study we aim to enroll hypotensive trauma patients and study factors of prehospital rescue that can be associated with in-hospital mortality and recovery, eventually even with hospital outcome. For each patients data as demographic, kind of trauma (mechanism, injury scores), therapies and maneuvers will be recorded and then analyzed in comparison with in-hospital data such as need for transfusion, ABG parameters, length of stay (in-ward and ICU), need of therapies like invasive ventilation and renal replacement therapy, recovery and outcome
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years
- •Witnessed traumatic event managed by HEMS
- •Shock at first evaluation (Systolic blood pressure < 90 mmHg)
- •Suspect or obvious ongoing haemorrage
排除标准
- •Patients in cardiac arrest at HEMS arrival in which resuscitation is not started or interrupted by HEMS crew
研究组 & 干预措施
Trauma patients in shock
The study focuses on hypotensive trauma patients assisted by HEMS teams
干预措施: Drugs administration (Drug)
Trauma patients in shock
The study focuses on hypotensive trauma patients assisted by HEMS teams
干预措施: Resuscitative endovascular balloon occlusion of the aorta (Device)
Trauma patients in shock
The study focuses on hypotensive trauma patients assisted by HEMS teams
干预措施: Blood transfusions (Biological)
Trauma patients in shock
The study focuses on hypotensive trauma patients assisted by HEMS teams
干预措施: Prehospital management (Other)
Trauma patients in shock
The study focuses on hypotensive trauma patients assisted by HEMS teams
干预措施: Prehospital eFAST (Device)
结局指标
主要结局
30 days mortality
时间窗: 30 days
次要结局
- survival from prehospital to hospital admmission(1 day)
- Hospital length of stay(6 months)
- Transport time(24 hours)
- Blood products transfused during the first 24 hours after hospital admission(24 hours)
