Carbapenem Antibiotic Therapy for VIM Carbapenemase-Producing Enterobacteriaceae Infections
- Conditions
- Carbapenemase-Producing Enterobacteriaceae
- Registration Number
- NCT06185153
- Lead Sponsor
- University Hospital, Strasbourg, France
- Brief Summary
Carbapenemase-producing Enterobacteriaceae (CPE) infections are emerging infections that pose a therapeutic challenge. These infections mainly occur in patients with prolonged hospitalization and repeated exposure to antibiotics. Certain strains, notably VIM-producing strains, may remain sensitive to carbapenems. CPE VIM strains are rare in France, but represent the main CPE strains in many countries. They are historically the main type of carbapenemases isolated at the Strasbourg University Hospital.
- Detailed Description
The circulation of multi-antibiotic-resistant bacterial strains is significant at the Strasbourg University Hospital and the investigators wish to report their local experience in the use of carbapenems in infections with enterobacteria producing carbapenemase type VIM.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 70
- Adult patient (≥18)
- Treated at the HUS for a VIM-producing enterobacteria infection between 01/01/2011 and 11/30/2022
- Subjects who have not expressed their opposition to the reuse of their data for scientific research purposes.
- Patient having expressed his opposition to the retrospective reuse of his data for scientific research purposes.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mortality at 28 days Mortality at 28 days after infection
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Service des Maladies Infectieuses et Tropicales - CHU de Strasbourg - France
🇫🇷Strasbourg, France