A Questionnaire to Identify Predictive Symptoms and Risk Factors for Hydrogen and Methane Breath Testing Outcomes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,040
- 试验地点
- 1
- 主要终点
- Determine positive predictive symptoms for SIBO positive participants determined by HMBT
研究概览
简要总结
Lactulose HMBT and Glucose HMBT are simple non-invasive tests to assess whether imbalances in gut bacteria may be contributing to troublesome tummy symptoms. These imbalances in gut bacteria include small intestinal bacterial overgrowth (SIBO) and excessive methane production.
Recently there has been a lot of work to done by experts in the field, to ensure that performance and interpretation of these tests are standardised, to help improve the clinical utility of these investigations. Although there is a lot of information currently available demonstrating the risk factors and symptoms associated with these conditions, there is a lack of data demonstrating the factors that might lead to a positive test according to these new parameters. This study aims to collect data on symptoms and medical history, in patients referred for lactulose and glucose HMBT in order further improve the effectiveness of this test in the future.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participant is referred for and able to complete a postal Lactulose or Glucose HMBT according to protocol with The Functional Gut Clinic
- •Participant has capacity to understand written English
- •Participant can communicate well with the Investigator and to comply with the requirements for the entire study.
排除标准
- 未提供
结局指标
主要结局
Determine positive predictive symptoms for SIBO positive participants determined by HMBT
时间窗: At same time as breath test
Using the HMBTQ
次要结局
- Determine the frequency of recognised and potential risk factors in SIBO positive participants(At the same time as the breath test)
- Determine positive predictive symptoms for excessive methane positive participants determined by HMBT(At same time as the breath test)
- Determine the frequency of recognised and potential risk factors in excessive methane positive participants(At the same time as the breath test)
研究者
Dr Anthony Hobson
Clinical Director
The Functional Gut Clinic