Exercise Training as Medicine for Substance Use Disorder Patients

Not Applicable

Recruiting

• Conditions: Substance Use Disorders
• Interventions: Behavioral: low dose training; Behavioral: High dose training

• Registration Number: NCT04065334
• Lead Sponsor: St. Olavs Hospital

Brief Summary

This study compares the effects of high dose and low dose, high intensity, endurance training and strength training in substance use disorder patients. The hypothesis is that the increase in endurance (measured as maximal oxygen uptake) and strength (measured as maximal strength) will be similar in both the high dose and low dose training groups after 24 training sessions over eight weeks. The rationale for this assumption is based on the patient groups poor physical capacity, supporting that a lesser physical workload is needed to achieve a substantial increase in physical capacity. The practical implication could be higher training attendance, because it is likely easier to motivate the patient group when they only have to perform half the workload. It is paramount for this patient group to increase their physical capacity and consequently augment their physical health status since they are in a high-risk group for developing life-threatening lifestyle related diseases.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-08-21
• Study First Submitted QC: 2019-08-21
• Study First Posted: 2019-08-22
• Study Start: 2020-02-01
• Status Verified: 2023-01
• Last Update Submitted: 2023-01-11
• Last Update Posted: 2023-01-12
• Primary Completion: 2023-08
• Study Completion: 2023-08

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Being an inpatient at the clinic
• Free of known cardiovascular disease, pulmonary disease and cancer

Exclusion Criteria

• Not able to perform a maximal treadmill test
• Not able to perform a maximal strength test in hack squat

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
low dose training	low dose training	-
high dose training	High dose training	-

Primary Outcome Measures

Name	Time	Method
change in oxygen uptake	baseline to 8 weeks	cardiopulmonary exercise test (CPET) objective gas measurements
change in leg muscular strength	baseline to 8 weeks	One repetition maximum strength test half squat

Trial Locations

Locations (1)

Klinikk for rus- og avhengighetsmedisin, St Olavs Hospital; 🇳🇴 Trondheim, Norway