MedPath

EFFECTIVENESS OF SINGLE DOSE ORAL DEXAMETHASONE VERSUS MULTIDOSE PREDNISOLONE FOR TREATMENT OF ACUTE EXACERBATIONS OF ASTHMA AMONG CHILDREN ATTENDING THE EMERGENCY DEPARTMENT OF CHILDREN HOSPITAL, ISLAMABAD

Not Applicable
Conditions
Asthma in Children
Interventions
Registration Number
NCT05850143
Lead Sponsor
DR. MOHAMMAD ALI ARIF
Brief Summary

In this Study i'll compare the effectiveness of two drugs used in acute exacerbation of asthma by their sideffects, complaince and improvement in the PRAM score. The better one would be adapted in our clinical practice.

Detailed Description

Not available

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
192
Inclusion Criteria
  • i.Ages 2 to 12years ii. Previous history of asthma as diagnosed by a physician. iii. Presentation with acute exacerbation of asthma with symptoms of cough, wheeze, dyspnoea and oxygen saturation of less than 95% and with PRAM score of more than or equal to 6
Read More
Exclusion Criteria
  • i.Critical or life-threatening asthma i.e. patient with silent chest, cyanosis, drowsy, unable to verbalize, marked tachycardia and respiratory distress. ii.Known TB exposure iii.Fever more than 39. 5°C iv.Use of corticosteroids in previous 4 weeks v.Significant co-morbid disease: lung, cardiac, immune, liver, endocrine, neurological or psychiatric
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
FACTORIAL
Arm && Interventions
GroupInterventionDescription
Oral Single dose dexamethsone in acute exacerbation of asthmaDexamethasone-
Oral Multidose Prednisolone in acute exacerbation of asthmaPrednisolone-
Primary Outcome Measures
NameTimeMethod
Improvement in PRAM score4 days

PRAM will be evaluated at day 4

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Asim Nawaz Niazi

🇵🇰

Islamabad, Pakistan

Asim Nawaz Niazi
🇵🇰Islamabad, Pakistan
© Copyright 2025. All Rights Reserved by MedPath