NCT05850143Enrolling By Invitation不适用
EFFECTIVENESS OF SINGLE DOSE ORAL DEXAMETHASONE VERSUS MULTIDOSE PREDNISOLONE FOR TREATMENT OF ACUTE EXACERBATIONS OF ASTHMA AMONG CHILDREN ATTENDING THE EMERGENCY DEPARTMENT OF CHILDREN HOSPITAL, ISLAMABAD
DR. MOHAMMAD ALI ARIF1 个研究点 分布在 1 个国家目标入组 192 人开始时间: 2019年1月26日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 192
- 试验地点
- 1
- 主要终点
- Improvement in PRAM score
研究概览
简要总结
In this Study i'll compare the effectiveness of two drugs used in acute exacerbation of asthma by their sideffects, complaince and improvement in the PRAM score. The better one would be adapted in our clinical practice.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 2 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •i.Ages 2 to 12years ii. Previous history of asthma as diagnosed by a physician. iii. Presentation with acute exacerbation of asthma with symptoms of cough, wheeze, dyspnoea and oxygen saturation of less than 95% and with PRAM score of more than or equal to 6
排除标准
- •i.Critical or life-threatening asthma i.e. patient with silent chest, cyanosis, drowsy, unable to verbalize, marked tachycardia and respiratory distress. ii.Known TB exposure iii.Fever more than
- •5°C iv.Use of corticosteroids in previous 4 weeks v.Significant co-morbid disease: lung, cardiac, immune, liver, endocrine, neurological or psychiatric
研究组 & 干预措施
Oral Single dose dexamethsone in acute exacerbation of asthma
Active Comparator
干预措施: Dexamethasone (Drug)
Oral Multidose Prednisolone in acute exacerbation of asthma
Active Comparator
干预措施: Prednisolone (Drug)
结局指标
主要结局
Improvement in PRAM score
时间窗: 4 days
PRAM will be evaluated at day 4
次要结局
未报告次要终点
研究者
DR. MOHAMMAD ALI ARIF
Docter
Shaheed Zulfiqar Ali Bhutto Medical University
研究点 (1)
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