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临床试验/CTRI/2024/11/076278
CTRI/2024/11/076278尚未招募不适用

Effectiveness and Safety of use of Antiseizure medications for the primary and secondary prophylaxis of seizures in Acute Encephalitis Syndrome in tertiary care hospital centre – A Prospective Observational Study

All india institute of medical sciences, Raipur1 个研究点 分布在 1 个国家目标入组 53 人开始时间: 2024年11月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
53
试验地点
1
主要终点
Proportion of patient having no clinical seizure till time of discharge after initiation of treatment.

研究概览

简要总结

Encephalitis is an acute inflammation of brain parenchyma and/or meninges, associated with neurological dysfunction. The cause can be both infectious and non-infectious. Of the infectious causes, Viral Encephalitis is the most common cause. Seizures are the very common presentation of encephalitis . Currently there are no guidelines for use of antiseizure medications in these patients. Our study aims to find out whether these medication results in prevention of further seizures in encephalitis patients.

研究设计

研究类型
Observational

入排标准

年龄范围
14.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • Age more than 14 years Definite, probable or confirmed case of acute encephalitis syndrome as per WHO guidelines Patients prescribed antiseizure medications.

排除标准

  • Already taking ASM known case of epilepsy Undergone neurosurgical intervention With other presdisposing diseases.

结局指标

主要结局

Proportion of patient having no clinical seizure till time of discharge after initiation of treatment.

时间窗: every week till the time of discharge and at the end of 3 months.

次要结局

  • Proportion of patients having improvement in EEG at the end of 3 months after initiation of treatment as compared to baseline.(3 months)

研究者

申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Riya

AIIMS, Raipur

研究点 (1)

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