Predictors of Node Positivity in Endometrial Cancer

Not yet recruiting

• Conditions: Endometrial Cancer

• Registration Number: NCT05793333
• Lead Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Brief Summary

To investigate the role of histological and moleculr profile of endometrial cancer patietns in predicting the risk of nodal metastases in endoemtrila cancer patients.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-03-04
• Study First Submitted QC: 2023-03-29
• Study First Posted: 2023-03-31
• Status Verified: 2023-07
• Last Update Submitted: 2023-07-27
• Last Update Posted: 2023-07-28
• Study Start: 2023-08-10
• Primary Completion: 2023-12-31
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

• Written informed consent
• Histologically confirmed endometrila cancer
• Data on molecular genomic profiling (POLE mutated, p53 abnormalities, MMRd/MSI-H, and NSMP)
• Data on histological characteristics of the ttumor
• Execution of sentinel node mapping
• Data on sentinel node status (negative vs. positive)

Exclusion Criteria

• Stage IVB endoemtrial cancer
• consent withdraw

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
positive nodes	12 months	positive nodes detected by sentinel node mappinig

Trial Locations

Locations (1)

Fondazione IRCCS Istituto Nazionale dei Tumori; 🇮🇹 Milano, Lombardia, Italy