Management of Medication Related Osteonecrosis of the Jaws Using Piezosurgery With Simultaneous Double Periosteal Flap Closure
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- evaluation of pain
研究概览
简要总结
20 patients with MRONJ underwent surgical debridement using piezosurgery then closure using double periosteal flap
详细描述
20 patients with MRONJ underwent surgical debridement, crestal incision and oblique releasing incision were performed to expose the area of osteomyelitis, then squesterum was removed using piezosurgery. After complete debridement, the periosteal layer was dissected from mucoperiosteal buccal flap and based superiorly, then turn upward to be sutured to the lingual flap followed by suturing of buccal flap to achieve double layers closure
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •patients with MRONJ
排除标准
- •Patients had a history of radiotherapy
- •Patients need only conservative treatment
研究组 & 干预措施
management of medication related osteonecrosis of the jaw
The buccal mucoperiosteal flap was elevated to expose the area of osteonecrosis in the mandible. it was debrided using piezosurgery then closure was achieved using double periosteal flap
干预措施: management of medication related osteonecrosis of the jaw (Device)
结局指标
主要结局
evaluation of pain
时间窗: one month
visual analog scale (VAS), with 0 indicating no pain and 10 indicating the most severe pain.
wound healing
时间窗: one -3 months
the wound healing index (WHI) which scored soft tissue healing according to the following criteria: score 1 = uneventful healing with no gingival edema, erythema, suppuration, patient discomfort, or flap dehiscence; score 2 = uneventful healing with slight gingival edema, erythema, patient discomfort, or flap dehiscence, but no suppuration; and score 3 = poor wound healing with significant gingival edema, erythema, patient discomfort, flap dehiscence, or any suppuration
次要结局
未报告次要终点
研究者
mona samy sheta
lecturer of oral and maxillofacial surgery
Tanta University