Bloodstream Infections in Patients With Rheumatoid Arthritis

Completed

• Conditions: Rheumatoid Arthritis; Staphylococcus Aureus Bacteremia

• Registration Number: NCT03908086
• Lead Sponsor: Sabine Dieperink

Brief Summary

Study of incidence and risk factors of staphylococcus aureus bacteremia in patients with rheumatoid arthritis compared with the general population in a nationwide cohort of all adult members of the population from 1996 until 2017 using national registries

Detailed Description

Not available

Study Timeline

• Study Start: 1996-12-31
• Primary Completion: 2017-12-31
• Study Completion: 2017-12-31
• Status Verified: 2019-04
• Study First Submitted: 2019-04-03
• Study First Submitted QC: 2019-04-05
• Last Update Submitted: 2019-04-05
• Study First Posted: 2019-04-09
• Last Update Posted: 2019-04-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 6000000

Inclusion Criteria

• All members of the adult Danish population

Exclusion Criteria

• Staphylococcus aureus bacteremia prior to inclusion.
• Rheumatoid arthritis diagnosed prior to inclusion.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of staphylococcus aureus bacteremia	0-21 years
Incidence rate ratios	0-21 years	Comparing rheumatoid arthritis patients with the general population

Secondary Outcome Measures

Name	Time	Method
Risk factors of staphylococcus aureus bacteremia	0-21 years	Identification of risk factors both universal to both the general population and rheumatoid arthritis (RA) cohorts and RA disease specific factors (disease duration, disease activity, smoking, joint erosions, etc.)