Study Of Endobronchial Ultrasound Transbronchial Needle Aspiration (EBUS-TBNA) Cytology Of Enlarged Mediastinal & Hilar Lymph Nodes Detected In Interstitial Lung Disease

Sheba Medical Center1 site in 1 country30 target enrollmentMay 30, 2020

ConditionsInterstitial Lung Disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Interstitial Lung Disease
Sponsor: Sheba Medical Center
Enrollment: 30
Locations: 1
Primary Endpoint: assessing the findings of mediastinal/hilar LN sampling by EBUS-TBNA in patients with non-sarcoidosis ILD who demonstrate LN enlargement on chest imaging.
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of this study is to assess the findings of mediastinal/hilar LN sampling by EBUS-TBNA in patients with non-sarcoidosis interstitial lung disease ( ILD) who demonstrate LN enlargement on chest imaging. Patients with non-sarcoidosis ILD referred for bronchoscopy will undergo LN sampling by EBUS-TBNA. Cytology results will be recorded along with clinico-radiologic features, BAL findings, histology and final ILD diagnosis.

Registry

clinicaltrials.gov

Start Date

May 30, 2020

End Date

January 30, 2024

Last Updated

3 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Sheba Medical Center

Responsible Party

Principal Investigator

Dr. Liran Levy

Principal Investigator

Sheba Medical Center

Eligibility Criteria

Inclusion Criteria

•non-sarcoidosis ILD (low probably of sarcoidosis based on radiology),
•referred for bronchoscopy (BAL, TBLB or TBCB) in the Interventional Pulmonology Unit at Sheba Medical Center
•Patients with LN enlargement ≥1 cm in short diameter at stations 2, 4, 7, 10 or 11 (LN stations accessible to EBUS-TBNA)

Exclusion Criteria

•ILD with no indication to bronchoscopy
•contraindication to bronchoscopy .

Outcomes

Primary Outcomes

assessing the findings of mediastinal/hilar LN sampling by EBUS-TBNA in patients with non-sarcoidosis ILD who demonstrate LN enlargement on chest imaging.

Time Frame: during the procedure/surgery