CTRI/2022/11/047205
Not yet recruiting
未知
To develop NEAR AI, a model to predict response to immune checkpoint inhibitor therapy in Non Small Cell Lung carcinoma (NSCLC).
Kerala Startup Mission0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: C349- Malignant neoplasm of unspecifiedpart of bronchus or lung
- Sponsor
- Kerala Startup Mission
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Non small cell carcinoma lung of any histology who have received treatment with immune checkpoint inhibitor therapy between 2017\-2021\.
- •2\. Patients should have taken regular treatment as per prescribed protocol for at least 3 months or till first radiological response assessment by iRESIST, whichever is later.
- •3\. Drug treatments include Pembrolizumab/Nivolumab/Durvalumab/Atezolizumab either in combination with chemotherapy or as single agents.
- •4\. Stage IV or recurrent disease.
- •5\. Any line of treatment is included
- •6\. Combination with radiation is included
- •7\. Hematoxylin â?? Eosin slide with/without corresponding FFPE block of tumor biopsy tissue is available.
- •8\. Clinical record of response to ICI therapy is available.
Exclusion Criteria
- •1\. Documented infectious pneumonia during first 3 months of therapy.
Outcomes
Primary Outcomes
Not specified
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