ISRCTN47683043已完成不适用
A double blind cross-over trial to evaluate the effects of 5-40 mg/day simvastatin therapy on the endothelial function in young adults with familial hypercholesterolemia.
Academic Medical Center (Netherlands)0 个研究点目标入组 40 人开始时间: 2006年2月14日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Healthy heterozygous FH patients aged >18 years with a documented LDL receptor mutation and LDL cholesterol level above the 95th percentile for age and gender. Or LDL cholesterol above 95th percentile and a positive family history for FH or premature CAD.
排除标准
- •1. Females who are pregnant or intend to become pregnant
- •2. Hypersensitivity or contraindication to simvastatin
- •3. Excessive alcohol consumption, smoking or drug abuse
研究者
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