Short term efficacy of electroconvulsive therapy in treatment resistant schizophrenia

Government Medical College and Hospital Chandigarh0 个研究点目标入组 30 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1. Patients in the age group of 16 to 65 years. 2. Patients suffering from schizophrenia as per ICD 10.
•3. Patients who fulfilled the criteria for TRS. For the purpose of the study, TRS was defined according to the modified Kane et.al. criteria, which defines TRS as:
•a) At least two prior drug trials of at least 4-6 weeks duration at 400-600 mg of chlorpromazine (or equivalent) without significant clinical improvement.
•b) Persistent psychotic symptoms defined as a score of 45 on 18 item scale of BPRS and score of 4 (moderate) on at least two items of positive symptoms.
•c) The duration of illness should be at least one year.
•4. Patients who were accompanied by reliable informants.
•5. Patients and informants who were willing to participate in the study and who were ready to give consent for ECT and anesthesia.

•1. Patients who had associated medical problems, which could affect the course of illness as well as their fitness for general anesthesia.
•2. Patients of co-morbid substance dependence except nicotine dependence.
•3. Patients who had received ECT in the past one-year.
•4. Patients who had received at least 4 ECT?s in the past without any significant improvement.
•5. Patients who were intellectually deficient. 6. Patients having schizoaffective disorder.

发起方

Government Medical College and Hospital Chandigarh