NL-OMON28868已完成不适用
Infection prevention and immune modulation by bacterial lysates: gaining insight into the mechanism of an old therapy.
Investigator initiated trial by clinical researchers of the Department of Pediatrics and Department of Pulmonology; Franciscus Gasthuis & Vlietland, Rotterdam0 个研究点目标入组 75 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 75
研究概览
简要总结
to follow
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Subjects aged 12-60 years with proven asthma (airway responsiveness proven by reversibility or histamine PC20 < 8 mg/ml)) who have recurrent airway signs and symptoms despite optimal maintenance medication (medium/high dose inhalation corticosteroid and long-acting ¦Â2-agonist; GINA 4).
排除标准
- •-Other relevant respiratory conditions, e.g. OSAS, bronchiectasis
- •-Systemic immunological diseases/systemic immunosuppression
- •-Current smoking or past smoking > 10 pack years
- •-Other untreated co-morbidity, such as gastro-esophageal reflux disease, ENT problems, psychological disorders
- •-Non-compliance to current medication or inhalation technique
- •-Communication difficulties
- •-Pregnancy or planned pregnancy within 2 years
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