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Clinical Trials/NCT06958263
NCT06958263CompletedNot Applicable

Factors Associated With Sensitization in Patients With Chronic Low Back Pain

Karabuk University2 sites in 2 countries103 target enrollmentStarted: May 8, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
103
Locations
2
Primary Endpoint
Body awereness

Study Overview

Brief Summary

Chronic non-specific low back pain is a common health problem that significantly affects the quality of life of individuals. Increased pain intensity leads to deficiencies in the body's sensory organization, resulting in decreased awareness. This can lead to dysfunction in body awareness, which is known as the ability of individuals to perceive the sensations and conditions of their bodies. Body awareness plays a critical role in pain management and mobility. Chronic pain causes constant stimulation in the nervous system, causing central sensitization, which is when the central nervous system becomes overly sensitive to pain signals. As a result, a decrease in the pain threshold, constant pain, and increased muscle tension occur. Increased pain intensity and decreased awareness can result in a decrease in the maintenance of optimal functions, affecting muscular endurance. Inadequate muscular endurance can increase low back pain and make it difficult for individuals to perform their daily activities. Therefore, this study aims to examine the relationship between body awareness, central sensitization, disability, and muscular endurance in patients with chronic non-specific low back pain.

Detailed Description

Body awareness plays a critical role in pain management and mobility. Individuals with high body awareness can better manage their pain, which can contribute to a decrease in disability levels. Chronic pain causes constant stimulation in the nervous system, which causes central sensitization, which is when the central nervous system becomes oversensitive to pain signals. As a result, a decrease in the pain threshold, constant pain, and increased muscle tension occur. In addition, central sensitization can cause the body to be more vulnerable to injuries due to the body being in an overstimulated state. Increased pain intensity and decreased awareness can result in a decrease in the maintenance of optimal functions, affecting muscular endurance. Inadequate muscular endurance can increase low back pain and make it difficult for individuals to perform their daily activities. The literature has attempted to emphasize the relationship between pain, disability, and body awareness in various populations. However, the relationship between body awareness and central sensitization has not been sufficiently studied. Sensitization in the body as a result of central sensitization may be associated with changes in awareness. Understanding these complex relationships is important for developing appropriate treatment strategies in the rehabilitation and clinical follow-up process. Therefore, this study aims to investigate the relationship between body awareness, central sensitization, disability and muscular endurance in patients with chronic non-specific low back pain. Patients with chronic non-specific low back pain will be included in the study. Body awareness, central sensitization, pain intensity, muscular endurance and disability levels of the patients will be evaluated. The data obtained from the study will be analyzed appropriately.

Study Design

Study Type
Observational
Observational Model
Case Only
Time Perspective
Cross Sectional

Eligibility Criteria

Ages
18 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Being between the ages of 18-65
  • Being diagnosed with chronic non-specific low back pain (Pain between the gluteal folds and the 12th ribs that lasts at least 12 weeks and has no known pathoanatomical cause)
  • Being willing to participate in the study

Exclusion Criteria

  • Having a psychological disorder, mental disorder, cancer and severe depression
  • Having a history of primary or metastatic spinal malignancy, spinal fracture
  • Having a neurological disease (Hemiplegia, Multiple Sclerosis, Parkinson's, etc.)
  • Being diagnosed with advanced osteoporosis
  • Having a history of surgery or acute infection in the lumbar region

Outcomes

Primary Outcomes

Body awereness

Time Frame: Baseline

It will be measured with a body awareness survey. The total score varies between 18-126 and as the score increases, awareness increases

Pain pressure threshold

Time Frame: Baseline

Pressure pain threshold will be measured with an algometer in kg. High values indicate a high pain threshold.

Central sensitization

Time Frame: Baseline

Central sensitization will be assessed with the "Central Sensitization Scale". The total score range is between 0-100 points. As the score increases, sensitization increases and 40 points and above are considered higher sensitization.

Pain severity

Time Frame: Baseline

Pain intensity will be assessed with Vizüel Analog Scale (VAS). VAS varies between 0-10 and the higher the score, the greater the pain.

Disability levels

Time Frame: Baseline

Disability will be measured by the Oswestry Disability Index. The total score ranges from 0-100 and the higher the score, the higher the level of disability.

Low back awereness

Time Frame: Baseline

It will be measured with the Fremantle Waist Awareness Questionnaire (FBFA). The total score varies between 0-36 and the awareness decreases as the score increases

Trunk muscle endurance

Time Frame: Baseline

The Stabilizer Pressure Biofeedback Unit will be used to evaluate the multifidus muscle endurance. The time maintained at 40 mmHg pressure will be recorded. As the time increases, the endurance increases.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Karabuk University
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Musa Güneş

Principal Investigator, PhD

Karabuk University

Study Sites (2)

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