Comparision of three doses of oral gabapentin in reducing pain in patients undergoing gynecologic cancer surgeries
Not Applicable
- Conditions
- Health Condition 1: C53- Malignant neoplasm of cervix uteriHealth Condition 2: C54- Malignant neoplasm of corpus uteriHealth Condition 3: C562- Malignant neoplasm of left ovaryHealth Condition 4: C56- Malignant neoplasm of ovaryHealth Condition 5: C561- Malignant neoplasm of right ovaryHealth Condition 6: C569- Malignant neoplasm of unspecifiedovaryHealth Condition 7: C55- Malignant neoplasm of uterus, partunspecified
- Registration Number
- CTRI/2020/05/025131
- Lead Sponsor
- R KAVYA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients giving valid informed consent.
Patients aged between 18 â?? 65 years.
Patients belonging to ASA Grade l and ll.
Exclusion Criteria
1.Patients belonging to ASA Grade III and IV.
2.Pregnant patients.
3.Patients with known psychiatric disorders.
4.Patients on sedatives, hypnotics, antidepressant drugs.
5.Patients already taking oral Gabapentin.
6.Patients allergic to opioids and tramadol.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the efficacy of three different doses of oral Gabapentin given one hour prior to surgery as preemptive analgesic to attenuate postoperative pain in patients undergoing elective gynecologic oncological surgeries under General anaesthesia by measuring following <br/ ><br>parameters: <br/ ><br>heart rate(HR), <br/ ><br>systolic blood pressure(SBP), <br/ ><br> diastolic blood pressure(DBP), <br/ ><br>mean arterial blood pressure(MAP) , sedation score, <br/ ><br>VAS scoreTimepoint: VAS(Visual Analogue Score) score for postoperative pain will be noted at 0, 2, 4, 6, 8, 12, 16, 20, 24 hours postoperatively.
- Secondary Outcome Measures
Name Time Method To study and assess the degree of sedation with three different doses of Gabapentin using Ramsay sedation score. <br/ ><br>To study and assess the incidence of side effects like dizziness, nausea and vomiting with three different doses.Timepoint: 24 hours postoperatively