CTRI/2024/01/061610
Recruiting
N/A
Development and validation of a prediction tool for acute kidney injury in spontaneous Vs controlled ventilation patients with moderate to severe acute respiratory distress syndrome - NI
Faculty SEED grant- Manipal Academy of Higher Education0 sites0 target enrollmentTBD
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Health Condition 1: N178- Other acute kidney failure
- Sponsor
- Faculty SEED grant- Manipal Academy of Higher Education
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •ARDS patients who receive either oxygen therapy, non\-invasive ventilation or invasive ventilation (endotracheal or tracheostomy) within the first 24 hours of diagnosis.
- •Patients should have an acute decrease in ratio of partial pressure of arterial
- •oxygen to fraction of inspired oxygen of less than or equal to 200\.
- •Evidence of bilateral pulmonary infiltrates on a chest radiograph consistent with
- •C\-reactive protein levels less than 50mg per L
- •Bedside ultrasonogram confirming normal kidneys on admission.
Exclusion Criteria
- •No past history of kidney injury, obstructive nephropathy, pyelonephritis, circulatory
- •shock requiring vasopressors, cardio\-respiratory arrest or IV contrast which can
- •contribute to AKI.
- •No history of nephrotoxic drugs for the past 2 weeks
- •Patients with any mode of ventilation less than 24 hours received from outside hospital.
Outcomes
Primary Outcomes
Not specified
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