DRKS00030597招募中不适用
Metabolic health in neurodegenerative diseases - implications of metabolic characteristics and gut microbiome - NeuroBiom
Klinik und Poliklinik für Neurologie, Universitätsklinikum Bonn0 个研究点目标入组 100 人开始时间: 2023年2月7日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 50 Years 至 75 Years（—）
- 性别
- All
入选标准
- •BMI 18,5-39,9 kg/m²
- •Non-smoker (for at least 3 months)
- •written declaration of consent for participation in the study.
- •Diagnosis Parkinson disease or Alzheimer disease
- •PD based on clinical diagnosis according to Brain Bank criteria(Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson’s disease. A clinico-pathological study of 100 cases. JNNP 1992;55:181-184.)
- •Hoehn & Yahr stadium 1-3
- •Clinical and biomarker-based diagnosis with Alzheimer's pathology based on typical CSF findings
- •Mixed dementia with a vascular component (up to Fazekas II) is permitted.
排除标准
- •Taking medications that affect glucose metabolism
- •chronic hepatic diseases, gastrointestinal diseases, chronic inflammatory diseases or other severe diseases
- •antibiotic therapy 3 weeks before the start of the study
- •Planned lifestyle changes
- •regular intake of supplements
- •drug abuse
- •participation in another clinical trial simultaneously/in the last 30 days
- •Atypical PD syndromes
- •severe motor fluctuations
- •Dementia of unclear origin
- •Heavy vascular part (Fazekas III)
研究者
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