Creatine and GAA for Brain Oxygenation

Not Applicable

Completed

• Conditions: Oxygen Deficiency
• Interventions: Dietary Supplement: Supplement; Dietary Supplement: Placebo

• Registration Number: NCT06371651
• Lead Sponsor: University of Novi Sad, Faculty of Sport and Physical Education

Brief Summary

The main aim of this randomized controlled trial is to evaluate cerebral blood oxygenation after 7-day administration of a creatine-guanidinoacetic acid (GAA) mixture in healthy adults before, during, and after a series of cognitive tests.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-03-01
• Primary Completion: 2024-04-10
• Study Completion: 2024-04-12
• Study First Submitted: 2024-04-14
• Study First Submitted QC: 2024-04-14
• Study First Posted: 2024-04-17
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-06
• Last Update Posted: 2024-05-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

• Age 18-30 years
• Absence of metabolic disorders or other health complications
• Provision of signed informed consent

Exclusion Criteria

• History of dietary supplement use within the preceding 4 weeks
• Lack of consent to randomization
• Concurrent participation in other studies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Supplement	Supplement	One sachet of supplement before breakfast and dinner
Placebo	Placebo	One sachet of inert compound before breakfast and dinner

Primary Outcome Measures

Name	Time	Method
Brain oxygen saturation	Change from baseline brain oxygen saturation at 2 weeks	Percentage of oxygen saturation in prefrontal brain

Secondary Outcome Measures

Name	Time	Method
Hemoglobin index	Change from baseline hemoglobin index at 2 weeks	Concentration of hemoglobin index in prefrontal brain

Trial Locations

Locations (1)

Applied Bioenergetics Lab at Faculty of Sport and PE; 🇷🇸 Novi Sad, Vojvodina, Serbia